We’ve recently replaced Rapid PREreviews with Structured PREreviews.
You can write a Structured PREreview now.
We’ll be updating older Rapid PREreviews like these soon.
| Question | Yes | Unsure | N/A | No |
|---|---|---|---|---|
| Are the findings novel? | 100% | 0% | 0% | 0% |
| Are the results likely to lead to future research? | 100% | 0% | 0% | 0% |
| Is sufficient detail provided to allow reproduction of the study? | 100% | 0% | 0% | 0% |
| Are the methods and statistics appropriate for the analysis? | 100% | 0% | 0% | 0% |
| Are the principal conclusions supported by the data and analysis? | 100% | 0% | 0% | 0% |
| Does the manuscript discuss limitations? | 33% | 0% | 0% | 67% |
| Have the authors adequately discussed ethical concerns? | 100% | 0% | 0% | 0% |
| Does the manuscript include new data? | 100% | 0% | 0% | 0% |
| Are the data used in the manuscript available? | 0% | 67% | 0% | 33% |
| Is the code used in the manuscript available? | 0% | 33% | 33% | 33% |
| Would you recommend this manuscript to others? | 100% | 0% | 0% | 0% |
| Do you recommend this manuscript for peer review? | 100% | 0% | 0% | 0% |
This paper explores metabolic reprogramming in Hepatocellular carcinoma via a novel hexokinase-containing domain 1 (HKDC1). There is over dependency of cancer cells on glucose consumption and this forms the popular therapeutic pathway. Hexokinases catalyse the rate-determining step in glucose…
This paper demonstrates the importance of HKDC1-mitochondrion interaction in hepatocellular cancer with sufficient data, suggesting a novel anticancer target.